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Functional imaging of the olfactory pathway in a new transgenic animal model.
Research goals and tasks:
The project is a collaboration between the University of Trento, the University of Düsseldorf, and the CNRS, Paris, to optimize and characterize the first transgenic honeybee model expressing a pan-neuronal calcium sensor (GCaMP6). This will allow minimally invasive functional imaging of 3D activity patterns and their dynamics at high spatial and temporal resolution using in vivo two-photon microscopy. It will grant simultaneous access to the entire brain to study neuronal correlates of a rich behavioural repertoire that includes odour discrimination and learning, navigation, and social communication.
The research fellow’s tasks will be, in collaboration with our partners, to optimize the maintenance of the recently generated first transgenic bee colonies and to contribute to the extension of the genetic toolkit. At the same time, she/he will conduct the first experiments of two-photon functional imaging in these transgenic bees to record and analyse activity patterns in different brain regions in response to different olfactory stimuli. Furthermore, she/he will perform the first continuous long-term imaging experiments to study olfactory learning and memory formation.
Duration of the fellowship: 24 months
· a PhD in biology, neuroscience, engineering, or related disciplines
· appropriate scientific curriculum, documenting the scientific and professional experience required to carry out the described research
· advanced experience in microscopy and postprocessing and analysis of imaging data
· experience in beekeeping is an advantage, the preparedness to learn it is required
· excellent English language skills
· via email to firstname.lastname@example.org
· attaching a CV and contact details to at least 2 references
Institution / Company: University of Trento
Department: Center for Mind/Brain Sciences - CIMeC
Closing Date of the Ad: 13/01/2021
Fully funded PhD position for UK/EU citizens:
How does stress affect floral smell preferences of bumblebees?
A funded PhD position is available for UK/EU citizens in the lab of Lena Riabinina (Durham, UK), in collaboration with Matt Tinsley (Stirling), Wayne Dawson (Durham) and Thomas Schmitt (Wuerzburg). The project How does stress affect floral smell preferences of bumblebees? will explore how bumblebees of different species use olfactory cues, and how this behaviour is affected by stress. The project will involve field collections of bumblebees and plants, behavioural assays and GC/MS analysis, in the UK and in Germany.
More details about the project are available here:
Information about IAPETUS2 PhD program is here:
Postdoctoral Researcher in Molecular Neurobiology / olfactory-mediated behavior,
A postdoctoral fellowship position is available (starting Winter/Spring 2021). Our laboratory investigates signal transduction mechanisms with the ultimate goal of elucidating the molecular and cellular events that modulate mammalian social behavior. Our main interest is to define the molecular, cellular and neural basis of basic olfactory-mediated social behaviors – from circuit characterization to behavioral relevance. In the recent years, we have pioneered the characterization of olfactory signaling mechanisms that have important implications in aggression, sexual behavior and predator recognition. Our multidisciplinary approach includes genetically modified mice, micro-endoscopic recordings in vivo, circuit tracing, high-resolution imaging, and behavior testing to manipulate and monitor the physiological properties of olfactory circuits and to address their functional role in the control of social behavior. The goal of this project is to investigate circuits underlying social behavior processing in mouse models using in vivo calcium imaging in awake-behaving mice and neuronal circuit tracing.
QUALIFICATIONS REQUIRED- We are looking for candidates with a Ph.D. degree in Biology or related discipline and advanced experience in modern techniques in neuroscience (neuroanatomy, viral vector use, molecular biology), as well as a strong publication record. A strong knowledge of genetic models, particularly mouse, and live-cell imaging, is an advantage. Excellent spoken and written English is indispensable. Funding for the positions is available, although application to independent funding will be encouraged.
Our Research Institute offers high quality innovative research experience, and outstanding well-equipped research facilities in an inspiring research environment.
Institution: INRAE Centre – Val de Loire
Department: Physiology of Reproduction and Behaviors
Closing Date of the Ad: 31/12/2020
Interested candidates please submit (in a single pdf) your application letter, CV, list of publications, and the names of two referees to Dr. Pablo Chamero: pablo.chamero-benito @inrae.fr
Two Research Fellow positions in Neuromorphic Olfaction
University of Hertfordshire, School of Physics, Engineering and Computer Science
College Lane Campus, Hatfield, University of Hertfordshire, UK
Fixed term until 13/8/2023.
Closing Date: 21st October 2020
Apply to join an interdisciplinary team of computational neuroscientists, AI researchers and computer scientists to investigate the neuro-computational principles of the sense of smell and translate them into approaches for machine and robot olfaction. Two positions are available, funded through the NSF/MRC NeuroNex grant “Odor2Action”, an international consortium of 16 world-leading research groups from the US, Canada, and the UK. The consortium will apply their joint expertise in computational and experimental neuroscience, behavioural studies, fluid dynamics, and fragrance chemistry to unlock how brains use natural stimuli to generate adaptive natural behaviours. The UH team will investigate real-time machine olfaction using biologically realistic spiking networks, on neuromorphic hardware, embodied in robots, performing olfactory navigation in real time. We will also use machine learning to analyse experimental data provided by collaborators and to gain a deeper insight into fragrance space.
Main duties & responsibilities
The successful candidate will join an interdisciplinary team to investigate the neuroscientific principles of the sense of smell and translate them into approaches for machine and robot olfaction. You will design and carry out research in collaboration with members of the group and project partners worldwide, publish your results, participate in meetings in the group and with the project partners and advise junior team members to carry out research.
Skills and experience needed. We are looking for candidates who have broad interests, but also have deep expertise in at least one relevant area, e.g. machine learning (including deep and recurrent networks), spiking network modelling, spiking neuromorphic platforms such as SpiNNaker, BrainScaleS, Loihi, Dynapse etc., or computational chemistry/cheminformatics. Previous exposure to robotic sensors and actuators and hands-on electronics is a plus. Experience in successfully establishing a programme of research, working collaboratively with other scientists, and disseminating results is essential as is mentoring and supervising junior research staff and students.
Qualifications required. A PhD or equivalent in a relevant subject or equivalent research experience in computational neuroscience, neuromorphic computing, machine learning, computer science or another relevant area is essential.
Research environment. The neuromorphic olfaction team is embedded in the Biocomputation Research Group, providing a rich and inspiring interdisciplinary research environment at the intersection of between Computer Science, Neuroscience, and Machine Learning. Computer Science research at UH excels in Biocomputation, Algorithms and Adaptive Systems/Robotics. We welcome diversity and equality in our team.
Postdoctoral Positions in "Pathogen Sensing" at Saarland University School of Medicine,
The Zufall and Leinders-Zufall labs are seeking Postdoctoral Researchers to join a highly interactive and innovative team to work primarily on the question of Pathogen Detection by Chemosensory Systems, using state-of-the-art technology and covering all levels of investigation from gene to behavior. For our recent publications on this topic, see Bufe et al. (2019) Nature Com, and Perniss et al. (2020) Immunity. We are now positioned to capitalize on these advances and make further contributions to this highly dynamic research field.
There will be many opportunities for collaboration and expanding your own repertoires of technologies using our network of international collaborators.
Requirements include a Ph.D. or equivalent with a strong background in Neuroscience, Physiology, Biophysics, or a related field. Knowledge and experience in optics, imaging, multi-neuron physiology, neural circuit analysis, in vivo physiology, and computational methods are a plus.
Apply by sending your CV and a brief statement of research interest to Frank Zufall, Center of Integrated Physiology and Molecular Medicine (CIPMM), Saarland University, 66421 Homburg, Building 48, Germany, Email: email@example.com or Trese Leinders-Zufall, Email: trese.leinders @uks.eu.
For the research topics of our groups see: Link
Please ensure that all application materials are received by December 15, 2020.